What city does the family in Family Guy live in? Question : What city does the family in Family Guy live in? Answer : The family in Family Guy live in Quahog. 7 little words Two-door Plymouth model Bruise around the eye Roosting rod 7 Little Words Easy mark 7 Little Words Hockey footwear 7 Little Words Hairstyle 7 Little Words Painter Jackson 7 Little Words 1940s Fairey aeroplane Kind of gull 7 Little Words Insignificant person 7 Little Words